What is it?
Andarine (S-4) is categorized as a SARM as well as a research chemical. S-4 was designed to treat several severe medical conditions, such as, muscle wasting, osteoporosis and benign prostatic hyptertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.
S-4 is an orally partial agonist for androgen receptors. Carrying this quality allows S4 to maintain and add lean body mass. When being compared to testosterone and other forms of steroids, the advantages of SARMS like S4, is they do not have androgenic activity in non-skeletal muscles. S4 is often thought of as the strongest SARM, in terms of the many capabilities it has. It is a lean body mass builder, as well as strength and vascularity enhancer.
How it work?
SARMS themselves bind to the AR (androgen receptor) and demonstrate osteo (bone) and myo (muscular anabolic activity. When something binds and activates the AR, it alters the expression of genes and increases protein synthesis, which in turn builds muscle.
SARMS cause muscle growth in the same method as steroids, the difference being that SARMS do not enhance the growth of ones prostate and other sexual organs. SARMS do not cause the many problems that anabolics can cause. SARMS do not have toxicity, in some circumstances only cause minimal suppression, allowing for a rapid recovery, as opposed to steroids that can cause long term problems from the high rates of suppression and provide a sense of well being each day that many steroids cannot cause.
A dose of 25 to 50 mg per day of Andarine(S4) is recommended. Each bottle contains 30+ days of use. 1 ml is 1/2 of the dropper or 25 mg. Cycle Length: 8 – 12 weeks.
Andarine (S-4) does not carry many side effects but there is often one well known side effect commonly associated with use. It sounds far more than it actually is so a deep understanding of it is required. Many researchers often report night vision problems when using S4. These are not permanent and only present with S4 use. In short, a metabolite of S4 binds to the receptor in the eye, causing a yellow tint to appear when switching from dark to lighted areas, especially prevalent in the evenings. It is impossible to gauge if/when/how it binds and how bad the effect can be. Some barely experience it at all while others can find it more difficult to manage.